Unilateral and illegal sanctions have ever been one of the domination system tools to press the Islamic republic of Iran. Today, Iran economics is experienced the special and unique economics event that has never been in the world until now. Therefore, ideology and innovation has been necessary to resolve the economic challenge from the experts when the special and no pattern condition has been created. According to these events, supreme leader proposed the resistive economy and referred in economic changing direction as important method. Resistive economy means to diagnose the pressure areas and subsequently attempts to control the nullify the impacts and prosperity these pressures. The purpose of the resistive economy is reconstruction and rehabilitation of national economy and adopting the strategies to utilize of local science and technology in Iran can be applied this theory. Thus, the role of national information network will be determined more than before. Today, according to statistics, global standard shows the extent of people access to technology including information technology and the percent of poverty or wealth of the nations in various dimensions. In many parts of the world, the poor classes have little access to information technology that meet only their primary needs; to meet their needs completely Hence, in this Book we discuss on national information network Connection & resistive economy & how can we reduce poverty by using IT.